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India Approves First Dengue Vaccine (Qdenga) – CDSCO Authorises Use for Ages 4‑60

On 21 July 2026, India’s CDSCO approved the first dengue vaccine, Qdenga, for people aged 4‑60 years. The live‑attenuated, WHO‑prequalified vaccine adds a new tool to the National Vector Borne Disease Control Programme’s fight against dengue, complementing existing vector‑control and surveillance efforts.
Overview On 21 July 2026 , the Union Health Ministry announced that India has granted its first marketing authorisation for a dengue vaccine. The approval was given by the CDSCO for the Qdenga . The vaccine will be imported by Takeda Biopharmaceuticals India Pvt. Ltd. and is intended for people aged 4 to 60 years. Key Developments Marketing authorisation granted after a thorough evaluation under the Drugs and Cosmetics Act, 1940 and Drugs Rules, 1945 . Vaccine is a live, attenuated tetravalent formulation produced in Vero cells . Two sub‑cutaneous doses of 0.5 ml each, given three months apart (0 and 3 months). Regulatory approval already secured in 42 countries and has WHO prequalification . Post‑marketing data from >24 million doses worldwide show a favourable safety profile. Important Facts The vaccine contains genetically modified organisms ( GMOs ) and is supplied as a freeze‑dried powder for reconstitution. Clinical development involved a global programme across more than eight countries, including Brazil, Thailand and Sri Lanka. A pivotal Phase III study in India evaluated safety and immunogenicity in the target age group. UPSC Relevance Understanding the role of the NVBDCP is essential for GS‑3 questions on public
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Key Insight

India’s first dengue vaccine approved – a boost to public‑health policy and regulatory action.

Key Facts

  1. 21 July 2026 – CDSCO ने Qdenga (Takeda) को मार्केटिंग ऑथराइज़ेशन दिया।
  2. वैक्सीन 4 से 60 वर्ष की आयु के लिए संकेतित है।
  3. मंजूरी Drugs and Cosmetics Act, 1940 और Drugs Rules, 1945 पर आधारित है।
  4. Qdenga एक लाइव‑एटेन्यूएटेड टेट्रावैलेंट वैक्सीन है जो Vero (बंदर किडनी) कोशिकाओं में उत्पादित किया गया है।
  5. दो सब‑क्यूटेनियस डोज़, प्रत्येक 0.5 ml, 0 और 3 महीनों पर दिए जाते हैं।
  6. WHO प्रीक्वालिफाइड है और पहले ही 42 देशों में मंजूर हो चुका है।
  7. 24 million से अधिक डोज़ के पोस्ट‑मार्केटिंग डेटा से एक अनुकूल सुरक्षा प्रोफ़ाइल दिखती है।

Background

Dengue is a major vector‑borne disease managed under the National Vector Borne Disease Control Programme (NVBDCP). The approval shows how India’s regulatory framework, international standards and domestic clinical trials converge to enhance health security and reduce disease burden.

UPSC Syllabus

  • Essay — Youth, Health and Welfare
  • Prelims_GS — Biology and Health
  • Essay — Science, Technology and Society

Mains Angle

GS‑3: Discuss the role of regulatory bodies like CDSCD and international agencies in strengthening India’s disease‑control programmes. Possible question – ‘Evaluate the impact of Qdenga’s approval on India’s dengue control strategy.’

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Overview

Full Article

Overview

On 21 July 2026, the Union Health Ministry announced that India has granted its first marketing authorisation for a dengue vaccine. The approval was given by the CDSCO for the Qdenga. The vaccine will be imported by Takeda Biopharmaceuticals India Pvt. Ltd. and is intended for people aged 4 to 60 years.

Key Developments

  • Marketing authorisation granted after a thorough evaluation under the Drugs and Cosmetics Act, 1940 and Drugs Rules, 1945.
  • Vaccine is a live, attenuated tetravalent formulation produced in Vero cells.
  • Two sub‑cutaneous doses of 0.5 ml each, given three months apart (0 and 3 months).
  • Regulatory approval already secured in 42 countries and has WHO prequalification.
  • Post‑marketing data from >24 million doses worldwide show a favourable safety profile.

Important Facts

The vaccine contains genetically modified organisms (GMOs) and is supplied as a freeze‑dried powder for reconstitution. Clinical development involved a global programme across more than eight countries, including Brazil, Thailand and Sri Lanka. A pivotal Phase III study in India evaluated safety and immunogenicity in the target age group.

Exam Relevance

Understanding the role of the NVBDCP is essential for GS‑3 questions on public

Read Original on hindu

India’s first dengue vaccine approved – a boost to public‑health policy and regulatory action.

Key Facts

  1. 21 July 2026 – CDSCO ने Qdenga (Takeda) को मार्केटिंग ऑथराइज़ेशन दिया।
  2. वैक्सीन 4 से 60 वर्ष की आयु के लिए संकेतित है।
  3. मंजूरी Drugs and Cosmetics Act, 1940 और Drugs Rules, 1945 पर आधारित है।
  4. Qdenga एक लाइव‑एटेन्यूएटेड टेट्रावैलेंट वैक्सीन है जो Vero (बंदर किडनी) कोशिकाओं में उत्पादित किया गया है।
  5. दो सब‑क्यूटेनियस डोज़, प्रत्येक 0.5 ml, 0 और 3 महीनों पर दिए जाते हैं।
  6. WHO प्रीक्वालिफाइड है और पहले ही 42 देशों में मंजूर हो चुका है।
  7. 24 million से अधिक डोज़ के पोस्ट‑मार्केटिंग डेटा से एक अनुकूल सुरक्षा प्रोफ़ाइल दिखती है।

Background & Context

Dengue is a major vector‑borne disease managed under the National Vector Borne Disease Control Programme (NVBDCP). The approval shows how India’s regulatory framework, international standards and domestic clinical trials converge to enhance health security and reduce disease burden.

UPSC Syllabus Connections

Essay•Youth, Health and WelfarePrelims_GS•Biology and HealthEssay•Science, Technology and Society

Mains Answer Angle

GS‑3: Discuss the role of regulatory bodies like CDSCD and international agencies in strengthening India’s disease‑control programmes. Possible question – ‘Evaluate the impact of Qdenga’s approval on India’s dengue control strategy.’

Analysis

Related PYQs

No related PYQs linked to this article yet.

Practice Questions

GS3
Easy
Prelims MCQ

Regulatory framework – Drugs and Cosmetics Act

1 marks
4 keywords
GS3
Medium
Mains Short Answer

International health standards and procurement

5 marks
4 keywords
GS3
Hard
Mains Essay / Case Study

Public‑health policy and programme implementation

20 marks
5 keywords
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India Approves First Dengue Vaccine (Qdeng... | UPSC Current Affairs