Union Minister Dr. Jitendra Singh launches India's first indigenous "CRISPR" based gene therapy for Sickle Cell Disease, which particularly affects India's tribal population

Nov 19, 2025
5 min read
75% UPSC
GS3
PIB - Press Releases

Key Points

  1. India launched its first indigenous CRISPR-based gene therapy for Sickle Cell Disease named 'BIRSA 101'.
  2. The therapy is dedicated to Bhagwan Birsa Munda, commemorating his 150th anniversary.
  3. CSIR-IGIB and Serum Institute of India signed a technology transfer agreement for affordable gene therapies.
  4. The therapy aims to contribute to a Sickle Cell Disease-free India by 2047.
  5. The CRISPR platform was developed at CSIR–Institute of Genomics & Integrative Biology (IGIB).

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